In the late Tokugawa Shogunate, Asa was born as the second daughter of a wealthy merchant in Kyoto, Japan. Later, in Osaka, Asa entered various business fields like coal mines, banks, life insurance. She also founded the first female university in Japan.
Botchan (Kazunari Ninomiya) has sense of strong justice and does not lie. He is offered a teaching job at a middle in a small village far away from his hometown of Tokyo. Botchan accepts the position and begins to work as a math teacher. The assistant principle there wields absolute power. Botchan has a hard time dealing with his fellow teachers and the students.
Takashi Hayama (Nijiro Murakami) is a third year high school student. He falls in love with Azusa Oribe (Akari Hayami) at first sight and they begin to date.
One day, Azusa tells Takashi "people who meet me, forget about me several hours later."
Takashi doesn't believe Azusa, but by chance he realizes that he forgot about Azusa. So he won't forget Azusa, Takashi begins to leave a note for himself and Azusa.
Sayaka (Mitsuki Takahata) works at a office. She's not very good at her job or with love. One night, she finds a man, Itsuki (Takanori Iwata), collapsed in front of her home. She takes him inside and they begin to live together. Itsuki teaches Sayaka about cooking wild herbs and collecting wild herbs, but he has a secret.
A postman learns that he doesn't have much time left to live due to a terminal illness. A devil then appears in front of him and offers to extend his life if he picks something in the world that will disappear. The man thinks about his relationships with ex-friends, ex-lovers, relatives and colleagues who will be sincerely sad when he dies.
Rena Sasaki (Keiko Kitagawa) is a beautiful woman with excellent memory and intelligence. She becomes a private detective and risks her life to chase down evil private detectives, because her younger sister was murdered by a stalker. The person that provided information to the stalker on her sister's location was a private detective.
Yusuke Serizawa (Keisuke Koide) works at a law office. He gets into a car accident. A woman helps him and she looks familiar to him, but he doesn't remember who she is. Yusuke Serizawa looks back at his past romances.
Haruya (Yuta Tamamori) is a university student. He is smart, brave and curious. Haruya then becomes involved in a case and investigates like a private detective. Since then, Haruya works like a private detective to solve cases.
Jun Hashimoto (Ren Kiriyama) is a sci-fi novel writer, but he isn't popular at all. He lives off of his savings. One day, his editor, Tateyama (Masanobu Sakata), assigns him a job. He is to write a short story for a web magazine oriented towards youths. The theme of the short story is "love." Jun Hashimoto at first refuses, because he has never written a love story before, but Tateyama pushes him to write the short story. The deadline is imminent. Jun's childhood friend Keisuke Murata (Shigeaki Kato) then appears in front of him. Jun complains to Keisuke that he can't write a love story. While talking to Keisuke, Jun comes up with an idea and begins to write his love story.
Makoto Tsugano (Keiko Kitagawa) is a medical intern. Recommended by physician Kojin Tsukuba (Ikko Furuya), whom she respects, Makoto Tsugano receives training at a forensics medicine classroom. There, she feels the classroom has a weird atmosphere. Professor Tojiro Kosaki (Kyohei Shibata) leaves the classroom and Makoto is alone in the classroom. She answers a phone call and hears a girl's voice asking "is that the place where autopsies are conducted?" The girl wants an autopsy performed on the body of a woman who died in a car accident. Her father was involved in the car accident. Even though the police conclude that an autopsy is unnecessary, Tojiro Kosaki presses ahead with the autopsy. Makoto doesn't understand Tojiro's excessive ways, but the autopsy reveals a hidden truth.