Hatoko (Mikako Tabe) goes back to her hometown of Kamakura for the first time in 8 years. She has inherited her grandmother's store "Tsubaki Stationery Store." The store actually functions to write beautiful letters on behalf of its clients. At first, Hatoko, being new to the business, seems like a rookie, but she begins to display her talent for writing letters. She gets more requests.
Kazuhisa Fukase (Tatsuya Fujiwara) graduated from a prestigious university, but he leads a boring life. His only strength is making delicious coffee. Whenever he makes coffee, he is reminded of his friend Yoshiki Hirosawa (Teppei Koike). He was friends with Yoshiki Hirosawa back in their university days, but Yoshiki Hirosawa died on a snowboarding trip 10 years ago.
One day, he meets Mihoko Ochi (Erika Toda) at a coffee shop. He is strongly attracted to her.
When Shoutarou Tatewaki first meets Sakurako Kujou, he knows his life will never be the same. Initially believing her to be responsible for a disappearance in the neighborhood, he later learns of her true talent: analyzing bone specimens. Sakurako has quite the collection of reconstructed animal bones, but she wishes she had more of the human variety, much to the chagrin of those around her.
Balsa (Haruka Ayase) tried to kill Rogusamu, but failed. 4 years later, Chagum (Mizuki Itagaki) becomes a crown prince of Yogo country. Due to her failure to kill Rogusamu, Balsa hides in the neighboring Rota Kingdom and works as a guard.
One day, Balsa saves a girl from human trafficking. The girl’s name is Asura (Rio Suzuki). God of Destruction Taruhamaya, which Asura’s ethnic group adore, stays in Asura’s body. Shaman daughter Shihana (Yoko Maki) and her father Sufaru (Akira Emoto) try to kill Asura. Balsa struggles to save Asura.
Yuka Shima (Mayu Matsuoka) works as an OL at a large general trading company. Suddenly, she is transferred from her office to an aquarium that is affiliated with her company. She now works as a keeper at the aquarium and her senior is Kaji (Kenta Kiritani). Yuka Shima struggles with her new job and marine animals, but with her bright personality she is able to grow as an aquarium keeper.
It is the Bunka-Bunsei period. While the culture of the townspeople matures and flourishes, administration by the close advisers of the 11th Tokugawa shogun Ienari is rampant and characterized by a debasement of public morals in Edo. Discontent with the samurai families and local businessmen grows because the lives of the ordinary people who live in the town are getting harder and harder. All of a sudden, a whistle sounds in the dead of the night. The chivalrous thief is known as Nezumi Kozo easily escapes along the roofs with a box of 1,000 ryo and scatters the money over a shabby tenement house that is asleep. The true identity of this thief is that of the playboy called Jirokichi. Although he is nothing more than a mere thief, he is obsessed about justice and would poke his nose in cases where he will not even get a penny. This is because he loves seeing the happiness of the people living in Edo.
Kotoha Ninomiya (Manami Higa) works in the general affairs department at a confectionery company. Suddenly, she receives an order to transfer to the public relations department. She has a hard time there. Making things worse, Kotoha Ninomiya learns that Atsushi Imagawa (Dai Watanabe), whom she holds secret feelings for, is about to marry another woman. They have been friends since they were young. Heart broken, she attends Atsushi’s wedding ceremony. At the ceremony, she is moved by Kumi Kuon’s (Kyoko Hasegawa) congratulatory speech. Kotoha Ninomiya is a legendary speech writer.
Makoto Tsugano (Keiko Kitagawa) is a medical intern. Recommended by physician Kojin Tsukuba (Ikko Furuya), whom she respects, Makoto Tsugano receives training at a forensics medicine classroom. There, she feels the classroom has a weird atmosphere. Professor Tojiro Kosaki (Kyohei Shibata) leaves the classroom and Makoto is alone in the classroom. She answers a phone call and hears a girl's voice asking "is that the place where autopsies are conducted?" The girl wants an autopsy performed on the body of a woman who died in a car accident. Her father was involved in the car accident. Even though the police conclude that an autopsy is unnecessary, Tojiro Kosaki presses ahead with the autopsy. Makoto doesn't understand Tojiro's excessive ways, but the autopsy reveals a hidden truth.
In the late Tokugawa Shogunate, Asa was born as the second daughter of a wealthy merchant in Kyoto, Japan. Later, in Osaka, Asa entered various business fields like coal mines, banks, life insurance. She also founded the first female university in Japan.